• Users Online: 266
  • Print this page
  • Email this page
Year : 2022  |  Volume : 5  |  Issue : 3  |  Page : 116-120

Chronic febrile respiratory illness with acino-nodular consolidations as presenting feature of granulomatosis with polyangiitis: A case report with review of literature

1 Department of Pulmonary Medicine, MIMSR Medical College, Latur, Maharashtra, India
2 Department of Internal Medicine, MIMSR Medical College, Latur, Maharashtra, India

Correspondence Address:
Prof. Shital Patil
Department of Pulmonary Medicine, MIMSR Medical College, Latur, Maharashtra
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/japt.japt_24_22

Rights and Permissions

Pulmonary tuberculosis (TB) is the most common cause for chronic febrile respiratory illness with constitutional symptoms in India being endemic and more prevalent in the nature of disease. Acino-nodular consolidations are documented in infective, inflammatory, autoimmune, and systemic vasculitis with pulmonary involvement. Pulmonary manifestations of systemic vasculitis have very diverse involvement ranging from nodule, consolidation, and cavitation. In this case report, a 40-year male, presented with constitutional symptoms such as persistent fever, anorexia, and minimal dry cough lung parenchymal consolidations. Patients' symptoms progressed over 4 months with poor response to empirical anti-TB treatment without mycobacterial microscopic or genome documentation in sputum. Bronchoscopy workups were inconclusive and tropical screens for bacterial, fungal, TB, and malignancy were negative. Clinical-radiological worsening and acinonodular masses with cavitation guide us to work for vasculitis panel and documented proteinase 3-antineutrophil cytoplasmic antibody positive with very highly raised titers. We have started on steroids with cyclophosphamide and observed excellent clinical and radiological response in 24 weeks.

Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded4    
    Comments [Add]    

Recommend this journal